Modified Ecstasy Compounds Have Powerful Anti-Cancer Properties ...

Altered forms of MDMA (Ecstasy) which are 100 times better at destroying cancer cells could be used to effectively treat patients with leukemia, lymphoma, and myeloma, according to an article in Investigational New Drugs. The authors, from the University of Birmingham, UK, explained that while Ecstasy is already known to have anti-cancer qualities, these modified forms of the drug are 100 times more powerful.

Ecstasy is the colloquial term for MDMA (3,4-Methylenedioxymethamphetamine), a drug that produces distinctive emotional and social effects (an entactogenic drug). It is a drug of the phenethylamine and amphetamine class. Ecstasy can reduce anxiety and induce euphoria and a sense of intimacy with others. In the majority of countries, the possession, manufacture and sale of MDMA is criminalized, except for some limited scientific or medical research purposes.

Scientists at the same research department at the University of Birmingham had already discovered that certain psychotropic drugs, such as Ecstasy, some antidepressants and weight-loss pills were effective in suppressing the development of white blood cancer cells.

The problem was that in order for those drugs to have any significant effect on cancer patients, the dosage would have to be so high that it would kill them. Hence, the researchers have spent the last six years trying to separate and isolate their cancer-busting properties so that patients could be spared being given the toxic ingredients. They worked with scientists from the University of Western Australia.

The Australian scientists created the new, modified compounds.

The British researchers found that these modified compounds were 100 times more powerful at combating cancer cells than Ecstasy. They say they also now understand the mechanism behind them.

Professor John Gordon, lead author, said:

?Together, we were looking at structures of compounds that were more effective. They started to look more lipophilic, that is, they were attracted to the lipids that make up cell walls. This would make them more ?soapy? so they would end up getting into the cancer cells more easily and possibly even start dissolving them.

By knowing this we can theoretically make even more potent analogues of MDMA and eventually reach a point where we will have in our drug cabinet the most potent form we could.?

This is an enormous step forward in their quest for an effective treatment for those with some forms of blood cancer, Professor Gordon added.

The modified forms of MDMA have not been tested on animals yet, because of the toxic effects they have on the brain and nervous system. In this study, the scientists added various molecular groups to the drug and then tested the MDMA analogues against B cell lymphoma cells (Burkitt?s lymphoma), and then against other B-cell lymphomas. They were able to observe how the compounds destroyed the cancer cells. Initially, their compounds were found to be 10 times as effective as MDMA. After adding other related compounds the effectiveness rose to 100 times more powerful than Ecstasy.

Gordon added:

?While we would not wish to give people false hope, the results of this research hold the potential for improvement in treatments in years to come.?

The scientists plan to progress to pre-clinical studies soon.

Dr. David Grant, Scientific Director of Leukaemia Lymphoma Research, a UK charity that helped fund this study, said:

?The prospect of being able to target blood cancer with a drug derived from Ecstasy is a genuinely exciting proposition. Many types of lymphoma remain hard to treat and non-toxic drugs which are both effective and have few side effects are desperately needed. Further work is required but this research is a significant step forward in developing a potential new cancer drug.?

Written by Christian Nordqvist

Copyright: Medical News Today

Not to be reproduced without permission of Medical News Today

Article source: View

Source: http://www.vidznet.com/modified-ecstasy-compounds-have-powerful-anti-cancer-properties/21267/

zsa zsa gabor dexter season 5 dexter season 5 toronto toronto miui zimbabwe news

Articles 20VN | Travertine Tiles - Improve Your Flooring ...

Today there are lots of people who are really searching for the better ways on how they can turn their home into something that they can be proud of. If you are going to make a search in the internet, there are lots of materials that you can use in order to make your home a haven of elegance and sophistication.

One of the most important parts of your home is your flooring. Most of the time when homeowner is making home improvement, flooring is usually taken for granted.

To make your flooring more sophisticated and elegant, you can use the travertine tiles during your home improvement. This tile is one of the most approachable materials that you can use in renovating your home. There are lots of people who prefer to use these tiles in making improvements for their home.

Travertine tiles holds an important place in the ancient history, these tiles are used in the development process of civilization from the Greek to the Roman Empire and up to now it is also being used by most homeowners. The development of this stone is similar with the marble tiles and mush similar to limestone in terms of development over thousand of years. It is very durable and attractive natural stone. This stone can give your home a classy look and eye catching look to the floor. Aside from using it for your flooring, there are some who use it in decorating your walls.

As you use the travertine tiles for your home decoration, it is important that you have already enough knowledge about these tiles. You can ask manufacturers or retailers about this stone. But if you want to have full information about these tiles, you can do your search through the internet. Through this you will be able to know about the negative and positive side of this building materials, It is important to know everything about the travertine so that you will be able to determine if it is suitable for your home use or not.

If you find travertine tiles suitable for your flooring, then you have to make sure that you hire someone that is knowledgeable when it comes in installing it. If there is something wrong with the way it this tiles is being installed then it will ruin your improvement project. It is important that the installer is expert when it comes in installing so that you will be successful with your improvement project.

Source: http://www.20vn.com/flooring/travertine-tiles-improve-your-flooring-ae4.htm

weather nyc ben bernanke shaq xom neiman marcus fed fx

Diageo full-year profit up 17 pct as margins rise (AP)

LONDON ? Diageo PLC, the world's largest maker of spirits, on Thursday reported a 17 percent rise in full-year profit, boosted by increased sales of higher-priced brands and a reduced tax bill.

For the year ending June 30, the maker of Johnnie Walker whisky and Guinness stout reported a profit of 1.9 billion pounds ($3.1 billion), up from 1.63 billion pounds a year earlier.

Sales rose 2 percent to 9.94 billion pounds. The tax rate fell from 21 percent to 14.5 percent.

The company raised its full-year dividend by 6 percent to 40.4 pence.

Diageo shares were up 4.9 percent at 1,173 pence as trading opened on the London Stock Exchange.

Chief Executive Paul Walsh forecast sales growth of 6 percent in the medium term.

"Medium-term guidance looks to be setting targets that are tough but achievable and also make Diageo look attractive as an investment proposition if achieved," said Phil Carroll, analyst at Shore Capital.

Diageo reported improved margins driven by a 24 percent increase in sales of premium "reserve brands" including Johnnie Walker, Kenel One vodka and Tanqueray No. 10 gin, and a 16 percent increase in sales of scotch in emerging markets.

Sales rose 3 percent in North America, 9 percent in Asia Pacific and 13 percent in other international markets. Sales in Europe dropped 3 percent, dragged down by lower sales in Greece, where sales dropped by a third, and an 18 percent decline in Spain and Portugal.

Diageo did not break out results for the second half of the year.

"We have strengthened the business, investing more behind our brands and in our routes to market and we have deepened our leading brand and market positions in the fastest growing markets of the world," Walsh said. "In addition we have implemented changes to drive further operational efficiencies."

Diageo reported spending 111 million pounds on a restructuring program announced in May, including 77 million pounds in payments to employees who were laid off.

Source: http://us.rd.yahoo.com/dailynews/rss/business/*http%3A//news.yahoo.com/s/ap/20110825/ap_on_bi_ge/eu_britain_earns_diageo

pba consumer reports consumer reports zachery tims funeral zachery tims funeral laser laser

Q&A: Solution to hair loss/baldness? | Hair Loss Blog

Solution to hair loss/baldness?You can try using Rogain or buy yourself a nice wig.

Personally, I?d just skip the trouble and get use to being bald.When you do go bald buy a nice wig.Sanju with such a handsome face you can get away with anything:shave it all off:one worry less.
PlanetsAccording to hair specialists shedding 70 to 100 strands of hair daily are normal. You just need to find out in the morning when you wake and also when you wash your hair to see if the amount of hair loss is more than normal. If it goes on for months you will be able to notice that you have less hair than before in certain area.

click below to read more :

http://www.trcb.com/health-and-fitness/hair-loss/hair-loss?a-few-tips-to-gain-a-full-head-of-hair-2902.htmYour hair is what you eat. If you eat correctly and drink enough water, 80 percent of your hair problems are solved. Eat a healthy and a balanced diet rich in protein and minerals. Oil your hair regularly, include a lot of milk, almonds and greens in your diet and drink at least 12 to 14 glasses of water daily. Check out http://usefulinfo-hairloss.blogspot.com/ for more info.m 21 year guy, my maternal side grandfather dint suffered any hairloss but my father and paternal grandfather are bald. My hairline at temples and forehead is receding and my hair density at top of my head is decreasing. please suggest me somethin that could stop this permamnently and also get back my lost hair.

Source: http://www.gohairloss.com/hair-loss/qa-solution-to-hair-lossbaldness.html

justin bieber and selena gomez break up justin bieber and selena gomez break up renee zellweger paul newman 49ers new york jets air france 447

Using a business administration degree to your advantage

A business administration degree is usually awarded after the completion of a 4-year course of study that focuses on statistics, accounting, information systems, management, human resources, finance, risk management and marketing. Graduates of business administration possess skills that are meant for a variety of employment opportunities that can help advance their careers in the future.

Completing a business administration degree will provide students the skills for a wide array of career paths. Such careers can be in areas like management, manufacturing, finance, sales, teaching, administration, publishing, banking, insurance, public relations and marketing. They will also be provided skills that will enable them to start a business of their own and manage the business effectively and efficiently.

Because a business administration degree is thorough and well-rounded, it gives graduates a certain degree of job security. If you possess such a degree, you will be well-trained to handle a wide variety of business situations and will be able to acclimate to new situations quickly.

A degree in business administration also carries with it a great deal of respect as graduates are viewed as experts in business. This is because, as students, they are given exposure to subjects that encompass all areas of business.

Whether you are interested in working for someone else or would like to start your own business, you will be provided the skills in areas like accounting, sales, management and much more. Skills in these areas will definitely set you apart from many other entrepreneurs because you have the necessary skills to open and successfully run their own company.

An associate?s degree in business administration will give students the knowledge base to be better qualified for many employment opportunities. It will also provide a solid foundation for getting further education.

A bachelor?s degree prepares graduates for entry-level careers in business. There are more and more businesses these days who hire only those who possess a bachelor?s degree. Positions in personnel resources, marketing, financial services, economics and sales are among the many career opportunities.

A graduate who wishes to obtain a master?s degree in business administration then the earning potential after the completion of the master?s degree goes up considerably. Many students opt for getting a doctorate in order to obtain lucrative positions. The thing is that specializing in a specific field tends to limit a person?s career options. Those who are able to choose not to specialize can have more opportunities that are open to them.

Holders of a business administration degree are in demand and the demand means that there are many job opportunities offering sizable income especially in the area of banking and finance where the most lucrative opportunities are available. There are also well-paying jobs in human resources, accounting and many other areas. Graduates also have the option of starting their own business or company.

People who are interested in getting a business administration degree have the option of getting the degree via the many colleges and universities that offer the courses. There are also many options available even for those who have multiple jobs and family commitments as they can opt for distance learning courses or online courses.

?

?

Source: http://businessdegreesite.com/2011/08/22/using-a-business-administration-degree-to-your-advantage/

chicago cubs weather radar rate rate speed speed rebecca black friday

Articles 20VN | Three Solid Money Making Ideas | work at home ...

Have you been trying to find a way to make some extra money? If you are looking for solid money making ideas, you will find many different opportunities online. When the Internet was invented, it opened up a whole new world for business. There are now thousands and thousands of various online businesses and you can be part of it. The following are three solid money making ideas to get you started.

Network Marketing
Network marketing involves selling the services or products of a business for a commission. When choosing these types of money making ideas, you will want to consider a few things. First of all, what is their commission structure? One business may offer you a commission of ten percent, while another will offer twenty-five percent. You will also want to look at whether or not they have a commission structure for any recruits you bring into the business. Some businesses will have it structured to pay you commissions on anything your recruits sells, as well. Before you join any network marketing business, you will also want to research how long they have been in business and whether or not they are a reputable business. The mistake many make is getting involved with businesses that are scams.

Online Auctions
Of all the money making ideas you will find, online auctions is one that is doing very well. If you have a knack for picking out products that others will buy, this is one you want to get more information on. With an online auction, you can list the products you wish to sell and set a base price that must be reached before it can sell. In other words, if you have a ring you want to sell for at least $10, set the base price for this amount and then the bidding can start. You may be surprised at how much certain items will sell for online. Once you get started, you may soon find yourself purchasing products at wholesale prices to list on your online auctions. Money making ideas such as this are a great way to get started.

Freelance Writing
If you have writing skills that are above average, you can use them to earn an income. Money making ideas like this one do take a lot of time and patience, but you will be able to make a lot of money if you have the right skills. There are many different article directories online where you can submit your articles. Some will pay you by a method known as pay-per-click. In other words, if someone opens your article page and clicks on one of the ads, you earn money. Others will pay you by pay-per-view. If someone opens your article page, you earn money. If you do not like these methods of payments, you will find many sites where you can sell your articles outright. Ghostwriting articles is also another strategy for selling your writing. Many people are willing to pay a lot of money for articles they can put their own name on.

Source: http://www.20vn.com/internet-businesses-online/three-solid-money-making-ideas-0eb.htm

words with friends words with friends marcos ambrose juicy couture juicy couture louisville co louisville co

How to Build & Monitor Highly Profitable PPC Advertising ...

Now, I am going to give you how to build, monitor and track your ppc advertising campaigns for maximizing profits or Return on Investment (ROI) online. You’ll discover how pay-per-click (ppc) campaign management software can help you to organize your ppc advertising campaigns and boost your profits online here.

Maybe you have an online business that markets a hot product that you are selling on your website; but you find that you are having trouble bringing customers into your site. So instead of gaining money, you are actually losing money because of the monthly rent that you?re paying to have your website hosted in cyberspace.

The best solution to this problem is to advertise in PPC. Let people know that you are here and ready to do business. One of the quickest and most effective ways to advertise your website on the net is to come up with a great Ppc campaign management software plan.

Certain keywords or phrases that people type into a search engine lead to hundreds and hundreds of search results that pertain to that specific keyword. Businesses that want to advertise on the net using a ppc advertising campaign have to come up with a plethora of keywords that is associated to the business that they are running; so when potential customers type in these keywords; it will lead them to their business site.

This is pretty much the whole concept that operates behind PPC. This is how a ppc advertising campaign brings in traffic to your site, with the selection of the right keywords that people can search through the net.

Some keywords tend to be more expensive than others, especially popular ones. It is vital to select the right keywords, in order to get your money?s worth. This is why it is important to manage you ppc advertising campaign wisely. Sometimes you are better off opting for the less popular keywords that are not so expensive, especially if you have a limited budget. Some businesses even hire the help of a consultant to manage their ppc advertising campaigns.

There are a lot of experts that specialize in Ppc campaign management software. They come with strategic plans, and assess the need of their clients. They then come up with a PPC advertising campaign that caters to their client?s specification.

]]>

This is why big home based internet marketing online businesses seek the expertise of a professional to run their ppc advertising campaign, because the right set of plans, can potentially bring in a large amount of profits. The more keywords you have, the more you increase the chances of customers clicking these keywords that would lead them to your website. There are also some software applications you can purchase, such as GoToast, or Bid Rank. These software applications track down your keywords listing.

Those ppc campaign management software tools are very easy-to-use for you to organize your ppc advertising campaigns. You can manage, monitor and track those ppc advertising campaigns closely. Personally, I believe that those ppc campaign management software applications are very valuable for internet entrepreneurs who are running or planning to run multiple ppc search engines and many ppc advertising campaigns.

If you are running a business online, and are planning to run a ppc advertising campaign, it is advisable to purchase keywords that are extremely related to the theme of your business. This way, people know what they are getting, and don?t get confused about the content of your website. The secret is to use keywords or phrases that are searched frequently, but cost very little.

The chances are, the longer people stay in your site, the likelihood of these potential customers making a transaction. But first thing is first. You must lure them into your turf.

This is why a lot of internet entrepreneurs spend a large amount of their budget on advertising, because they know that the right advertising campaign can start the ball rolling.

Also, you should do some research before you start your ppc advertising campaign. There are a lot of PPC search engines to choose from. Those who are less renowned charge less for the same keywords that you?d find in the bigger PPC search engines.

The great thing about ppc advertising campaigns is that you can reach a worldwide audience. Advertising online means global marketing.

Most PPC search engines require a monthly payment in exchange for their services. But if you fail to make payments, they will automatically take your listings out of their search engines. So make sure that you pay your monthly bills, so all the efforts that you put into your ppc advertising campaign don?t go to waste.

The potential earnings that can be generated by starting a pay per click campaign is significant. That?s why a lot of online businesses now are trying to get in on the act. Now, with the right set of keywords, and a smart Ppc campaign management software plan, more than ever, online businesses are bringing in the big bucks.

Final thoughts, managing and monitoring your ppc advertising campaigns well are the key to your success in ppc online advertising. Once you know what your weakness is in your ppc advertising campaigns, you can improve it effectively.

Learn more about how to do effective keywords for Ppc Online Advertising and your online business at: http://www.zKeywordTool.com. You’ll discover great keyword strategies to discover untapped niche keywords for your Ppc Online Advertising. Also, you’ll discover #1 best keyword analysis research tool for your Ppc Online Advertising.

Get a free report now at: http://www.zKeywordTool.com/free-report. You’ll discover great keyword search tips and secrets of how to do effective keywords for your home based online business. Also, you’ll save your time & money for minimizing your trail & error!

Learn more at: http://www.iPayByClick.com about the internet marketing online advertising PPC search engine and start earning big money on the internet at home now. You’ll discover great articles, news, tips, techniques and secrets of how to build highly profitable ppc campaigns.

*Reprint Policy: Reprint in full with writer?s name, contact information, active links and brief bio.

Siripong R. or zMillionDollars is a recognized authority on the subject of making money online from home through highly profitable & successful home based business. His websites, www.zMakeMoney.com and www.zMillionDollars.com, provide a wealth of informative articles and resources on everything you?ll ever need to know about earning money online.

Related Advertising Articles

.

Source: http://www.fashion-comments.com/archives/how-to-build-monitor-highly-profitable-ppc-advertising-campaigns-for-maximizing-profits-online_19973.html

europe europe diane lane toms stand by me lil b hitman